Getting My ceesdekker To Work
Getting My ceesdekker To Work
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2009, discovery of a fresh phenotype for microorganisms in slender nanofluidic slits; and to start with detection of area protein constructions alongside DNA making use of reliable-condition nanopores
Our team reports bacterial cell division and is aiming to represent a ‘bottom up biology’ in synthetic cells that can autonomously divide. Our most important desire lies in cell division, chromatin structure, and spatial Command.
Multicolor imaging of the bacterial nucleoid and mobile division proteins with blue, orange, and in close proximity to-infrared fluorescent proteins
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
This yielded a breakthrough. Within just only a few months, we were being capable to evaluate transport as a result of someone single-walled carbon nanotube. Determined by low-temperature experiments by an excellent PhD student in my team, Sander Tans (now a valued colleague and professor at Delft College of Technological innovation having an Energetic investigate lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with quite long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes
Many associated developments followed, exactly where our group established various transistor variants like single-electron transistors at space temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled numerous transistors into tiny proof-of-principle Digital circuits.
Dynamic ParB–DNA interactions initiate and retain a partition condensate for bacterial chromosome segregation
In 1993, to be a young and eager affiliate professor at Delft College of Technology, I had to begin with concentrated the study initiatives of my team on measuring the electrical conductance of only one conducting-polymer molecule. Inside two several years, we experienced established a device during which an individual wire of the phthalocyaninepolysiloxane polymer was connected in between two carefully spaced steel nanoelectrodes.
But carbon nanotubes have remained a investigate matter of appreciable fascination to several. Certainly, the outlook on utilizing carbon nanotubes to construct sensible devices, in spots which include radio-frequency electronics, electronic electronics and flexible electronics, remains dazzling.
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
2001, discovery of solitary-electron transistors at space temperature determined by nanotubes; realization of initially logic circuits with carbon nanotube products; and discovery with the molecular composition of DNA maintenance enzymes with AFM
Developments in nanotechnology in the nineteen nineties made developing electronic devices from single molecules a possibility. Cees Dekker recounts how his team created a room-temperature transistor according to just one carbon nanotube.
2004, discovery of recent physics in translocation of DNA as a result of nanopores; 1st experimental research of ions conduction in https://www.ceesdekker.net nanofluidic channels; first electrochemistry with unique solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; initial biophysics characterization of your mechanical Homes of double-stranded RNA; and initial one-molecule research of DNA translocation by a restriction-modification enzyme.